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Georgios Papanikolaou Georgios Nikolaou Papanikolaou  (or  George Papanicolaou   / ˌ p æ p ə ˈ n ɪ k ə l aʊ / ;  Greek :  Γεώργιος Ν. Παπανικολάου   [papanikoˈlau] ; 13 May 1883 – 19 February 1962) was a Greek pioneer in  cytopathology  and early cancer detection, and inventor of the " Pap smear ". After studying medicine in Greece and Germany, he migrated in 1913 to the United States. He first reported that uterine cancer cells could be detected in vaginal smears in 1928, but his work was not widely recognized until the 1940s. An extensive trial of his techniques was carried out in the early 1950s. In 1961 he was invited to the  University of Miami  to lead and develop the Papanicolaou Cancer Research Institute there. Life Papanikolaou's house in Kymi Born in  Kymi, Greece , Papanikolaou studied at the  University of Athens , where he received his medical degree in 1904. Six years later, he received ...